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Scyliorhinin II
CAS No. 112748-19-3
Scyliorhinin II( —— )
Catalog No. M30549 CAS No. 112748-19-3
Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 190 | Get Quote |
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| 10MG | 311 | Get Quote |
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| 25MG | 624 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameScyliorhinin II
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NoteResearch use only, not for human use.
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Brief DescriptionScyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.
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DescriptionScyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.(In Vitro):Scyliorhinin II is a neurokinin-3 selective tachykinin receptor, with a Ki of 2.5 nM for neurokinin-3 (NK-3) receptor in rat cerebral cortex. Scyliorhinin II has little effect on NK-1 and NK-2 receptors, with Ki (NK-1 receptor)/Ki (NK-3 receptor) and Ki (NK-2 receptor)/Ki (NK-3 receptor) of 176 and 200.(In Vivo):Scyliorhinin II produces potent, dose-related reciprocal hindlimb scratching about equipotently with an ED50 of 0.08 nmol via intracerebroventricularly (i.c.v.) administration in mice.
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In VitroScyliorhinin II is a neurokinin-3 selective tachykinin receptor, with a Ki of 2.5 nM for neurokinin-3 (NK-3) receptor in rat cerebral cortex. Scyliorhinin II has little effect on NK-1 and NK-2 receptors, with Ki (NK-1 receptor)/Ki (NK-3 receptor) and Ki (NK-2 receptor)/Ki (NK-3 receptor) of 176 and 200.
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In VivoScyliorhinin II produces potent, dose-related reciprocal hindlimb scratching about equipotently with an ED50 of 0.08 nmol via intracerebroventricularly (i.c.v.) administration in mice.
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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RecptorKi: 2.5 nM (Neurokinin-3 receptor)
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Research Area——
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Indication——
Chemical Information
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CAS Number112748-19-3
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Formula Weight1851.09
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Molecular FormulaC77H119N21O26S3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:Ser-Pro-Ser-Asn-Ser-Lys-Cys-Pro-Asp-Gly-Pro-Asp-Cys-Phe-Val-Gly-Leu-Met-NH2
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Buck SH, et al. The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors. Eur J Pharmacol. 1987 Nov 24;144(1):109-11.
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